I would have never guessed. Owen asks Cristina on a date and then shows up late and drunk. Meredith tells Derek that her roommates are her family and he's not kicking them out. Derek tells Meredith's roommates that he is moving in so they have to move out. Callie and Mark go get a drink and he gives her advice about dating women.Owen Hunt begins work at the hospital and at first Cristina hides from him, but when he sees her, it seems he doesn't remember her. Season 5 Episode 16,"An Honest Mistake" Izzy is told about the mix-up with her results and a patient's and learns she has cancer. Alex uses Izzie's modeling against her, and her last ad causes a patient to reject her care. Meredith tells Derek that he has to be on her side and he talks to the chief, who then talks to Meredith and says he is sorry that she was neglected as a child. A dying boy needs a transplant and Bailey tries to get it from the death row patient, asking Shepherd to kill him. Bailey suggests that he give up his wedding day for Alex and Izzie. Toeing the line between romantic and tragic, this episode begins with Izzie slowly losing her memory after her cancer surgery and everyone realizing that the … Izzie tries to draw her own blood, but can't do it, so she has her interns "practice" on her. Izzie appears in the first episode of Grey's Anatomy, meeting fellow interns Meredith Grey, Cristina Yang, Alex Karev, and George O'Malley. Alex: One inappropriate woman. At the hospital, Sadie talks the interns into taking out her appendix, and when there are complications, Lexie gets Meredith. While 300 episodes are something Grey's fans should celebrate, we're a little nervous to see what showrunners Shonda Rhimes and Krista Vernoff have planned for the big finale for the 300th. He ends up in Denny's old room and Izzie sees Denny and he talks to her.The interns practice on each other and then cadavers until they are caught. He says okay.George is set to retake his intern exam but helps Webber with a flood in the hospital caused by a burst pipe. He wants Cristina's support, but she says she doesn't want him to die and can't support him. But when Izzie's brain cancer diagnosis takes a turn for the worse, Derek and Meredith decide to give Izzie and Alex their ceremony, and instead get married by writing their vows on a post-it. Grey's Anatomy Promo: Meredith Does Community Service! Then she has the interns look at her labs, saying they are for Patient X.Cristina works with an older doctor whom she believes needs to retire. Cristina is impressed when an Army doctor comes in and stables his own leg wound. Denny tells Izzie that he's real and they have sex. Toeing the line between romantic and tragic, this episode begins with Izzie slowly losing her memory after her cancer surgery and everyone realizing that the terribly injured patient, 007, is George. Callie has Mark teach her how to have sex with women. It just, it never occurred to me that she would ever be with anyone else. He says she needs her own place too and gives her the trailer. Izzie, who was having hallucinations of her dead fiance, Denny Duquette (Jeffrey Dean Morgan), earlier in the season, learned the bad news after asking the … Dixon has a panic attack and tells Cristina to hug her to slow down her nervous system. Meredith thinks Cristina didn't choose her because they are fighting over the intern thing, but Cristina says it's not true. Derek won't come to work after making a mistake that killed a woman. Episode: 24. Cristina and Meredith are still fighting because Meredith didn't stand up for Cristina when she got in trouble for the interns doing procedures on each other. Izzie encountered Hannah's parents at Seattle Grace Hospital and found outthat she had leukemia. Seattle took a heavy toll on Izzie. Don't be spooked. Grey's Anatomy Spoilers: Izzie's Cancer Revealed. She decides to stay with Arizona. Later she asks him and he says that there were twenty in his unit that went to Iraq. You left me. Follow him on Google+ or email him here. Izzie Stevens and Alex Karev Season 5, Episode 22 “What a Difference a Day Makes” The vibe: Izzie’s idea of a perfect wedding turns out to be Magical Garden Inside a Big Church. Owen tells Cristina that even though she was right, she was a bully about it.Derek and Addison disagree over their patient. Izzie and Cristina do a secret autopsy and Bailey catches them. Thursday, the series finally explained the character's departure. Meanwhile, John Doe suffers complications from the earlier surgery and a CT shows a re-bleed so he requires more surgery. Derek and Mark have an argument over a patient, but Derek comes to see that Mark really is a good doctor. O'Malley is not going to get over this. Alex learns his fate after re-taking his medical exams. She talks to Lexie and decides that she is a good person and tells Mark that she likes her. If you’re not a fan of Grey's Anatomy spoilers, avert your eyes. The chief tells Meredith to get him back and that he was going to propose. I make no apologies for how I chose to repair what you broke. The episode ended with a montage of scenes recapping Alex and Izzie's romance. He never thought she would use them, but she did and she had twins: Eli and Alexis. Season 6 focused on Izzie's battle with stage VI skin cancer, which she managed to recover from despite the worst of odds. Owen has another PTSD episode that leads him to strangle Cristina, which traumatizes her and leads to her breaking up with him. Owen takes Cristina down to the basement where there is a vent that blows a lot of air and kisses her. Webber coerces a woman into donating her husband's organs. Callie's father shows up and gives her an ultimatum. Alex and Izzie decide to be exclusive.Hahn cries after sex saying that sex with Callie is so much better than with a man. At the same time Izzie is trying to stop Alex from making stupid decisions Meredith and Cristina lie to each other and themselves about their relationships with McDreamy and Burke, respectively. Grey’s Anatomy has seen many characters leave, mostly those from season 1, and among those is Katherine Heigl’s Izzie – and here’s why she left. Yes, you read that correctly, Alex Karev has left Seattle to be with Izzie Stevens. Webber offers him a job, but he says he has to get back out on the field. And I wrote that episode… She finally figures out that she is dying and he's there to take her away. They get into a fight and Hahn says that Callie is not a lesbian and then she walks away. Izzie's mom comes after Bailey calls her. Last night was Dr. Alex Karev's final episode on 'Grey's Anatomy,' and fans are so angry about how the show wrote him off that they would have rather seen him die. The chief pediatric surgeon has a heart attack and dies, and Arizona Robbins is brought in. Izzie finds an apartment and asks Alex to move in with her, but he says he'd rather live in his car.